Advanced Multi-Linc analysis to clarify circuit mechanisms of cortical and subcortical functions

We are aiming to develop the 'Multi-Linc' method, which allows us to analyze spike activity of multiple neurons whose axonal projections are identified optogenetically. So far, we have established the basic technology and showed its potential usefulness in cortex and basal ganglia researches. For practical applications, we will further automatize and increase the scale by improving real-time computer controls.