The ultrastructural identification of translatable biomarkers for the diagnosis of the early stages of Parkinson’s disease and related disorders

By ultrastructural analyses of the organelles, axons and synaptic terminals of the murine models of Parkinson’s disease (PD) and related disorders, we are trying to identify translatable biomarkers for the earlier diagnosis of these disorders. On the basis of the results obtained from these mouse models，we are going to develop ultrastructural analytical methods that enable to identify translatable biomarkers from Marmoset monkey models of PD.