Molecular and functional architecture imaging in marmoset brain

To clarify the relationship between molecular and functional network in the brain and the pathology or social behavior, we will perform fusion analysis of functional network image by fMRI and neurotransmission image by PET, and will establish the method for quantitative molecular and functional architecture imaging. By analyzing a variety of disease model marmosets, which were varied with specific neural networks and neurotransmission function by drug administration or genetic modification, we will extract the “imaging biomarkers” which are translatable to human psychiatric and neurological disorders as “intermediate phenotype”.