研究業績

Glucocerebrosidases catalyze a transgalactosylation reaction that yields a newly-identified brain sterol metabolite, galactosylated cholesterol

Akiyama H, Ide M, Nagatsuka Y, Sayano T, Nakanishi E, Uemura N, Yuyama K, Yamaguchi Y, Kamiguchi H, Takahashi R, Aerts J, Greimel P, Hirabayashi Y

Identification of calcium and integrin‐binding protein 1 as a novel regulator of production of amyloid β peptide using CRISPR/Cas9‐based screening system

Chiu Y, Hori Y, Ebinuma I, Sato H, Hara N, Ikeuchi T, Tomita T

Variants in saposin D domain of prosaposin gene linked to Parkinson’s disease

Oji Y, Hatano T, Ueno S, Funayama M, Ishikawa K, Okuzumi A, Noda S, Sato S, Satake W, Toda T, Li Y, Hino-Takai T, Kakuta S, Tsunemi T, Yoshino H, Nishioka K, Hattori T, Mizutani Y, Mutoh T, Yokochi F, Ichinose Y, Koh K, Shindo K, Takiyama Y, Hamaguchi T, Yamada M, Farrer M, Uchiyama Y, Akamatsu W, Wu Y, Matsuda J, Hattori N

Pathogenic POGZ mutation causes impaired cortical development and reversible autism-like phenotypes

Matsumura K Seiriki K Okada S Nagase M Ayabe S Yamada I Furuse T Shibuya H Yasuda Y, Yamamori H, Fujimoto M, Nagayasu K, Yamamoto K, Kitagawa K, Miura H, Gotoda-Nishimura N, Igarashi H, Hayashida M, Baba M, Kondo M, Hasebe S, Ueshima K, Kasai A, Ago Y, Hayata-Takano A, Shintani N, Iguchi T, Sato M, Yamaguchi S, Tamura M, Wakana S, Yoshiki A, Watabe A, Okano H, Takuma K, Hashimoto R, Hashimoto H, Nakazawa T

Reduced Auditory Mismatch Negativity Reflects Impaired Deviance Detection in Schizophrenia

Koshiyama D, Kirihara K, Tada M, Nagai T, Fujioka M, Usui K, Araki T, Kasai K

Visualization of AMPA receptors in living human brain with positron emission tomography

Miyazaki T, Nakajima W, Hatano M, Shibata Y, Kuroki Y, Arisawa T, Serizawa A, Sano A, Kogami S, Yamanoue T, Kimura K, Hirata Y, Takada Y, Ishiwata Y, Sonoda M, Tokunaga M, Seki C, Nagai Y, Minamimoto T, Kawamura K, Zhang M, Ikegaya N, Iwasaki M, Kunii N, Kimura Y, Yamashita F, Taguri M, Tani H, Nagai N, Koizumi T, Nakajima S, Mimura M, Yuzaki M, Kato H, Higuchi M, Uchida H, Takahashi T

Resting-state EEG beta band power predicts quality of life outcomes in patients with depressive disorders: a longitudinal investigation

Koshiyama D, Kirihara K, Usui K, Tada M, Fujioka M, Morita S, Kawakami S, Yamagishi M, Sakurada H, Sakakibara E, Satomura Y, Okada N, Kondo S, Araki T, Jinde S, Kasai K

Store-Operated Calcium Channels Are Involved in Spontaneous Slow Calcium Oscillations in Striatal Neurons

Kikuta S, Iguchi Y, Kakizaki T, Kobayashi K, Yanagawa Y, Takada M, Osanai M

Visualization of Brain Activity in a Neuropathic Pain Model Using Quantitative Activity-Dependent Manganese Magnetic Resonance Imaging

Inami C, Tanihira H, Kikuta S, Ogasawara O, Sobue K, Kume K, Osanai M, Ohsawa M

α-Synuclein BAC transgenic mice exhibit RBD-like behaviour and hyposmia: a prodromal Parkinson’s disease model

Taguchi T, Ikuno M, Hondo M, Parajuli L, Taguchi K, Ueda J, Sawamura M, Okuda S, Nakanishi E, Hara J, Uemura N, Hatanaka Y, Ayaki T, Matsuzawa S, Tanaka M, El-Agnaf O, Koike M, Yanagisawa M, Uemura M, Yamakado H, Takahashi R

White matter microstructural alterations across four major psychiatric disorders: mega-analysis study in 2937 individuals

Koshiyama D, Fukunaga M, Okada N, Morita K, Nemoto K, Usui K, Yamamori H, Yasuda Y, Fujimoto M, Kudo N, Azechi H, Watanabe Y, Hashimoto N, Narita H, Kusumi I, Ohi K, Shimada T, Kataoka Y, Yamamoto M, Ozaki N, Okada G, Okamoto Y, Harada K, Matsuo K, Yamasue H, Abe O, Hashimoto R, Takahashi T, Hori T, Nakataki M, Onitsuka T, Holleran L, Jahanshad N, van Erp T, Turner J, Donohoe G, Thompson P, Kasai K, Hashimoto R

Structurally distinct α-synuclein fibrils induce robust parkinsonian pathology

Hayakawa H, Nakatani R, Ikenaka K, Aguirre C, Choong C, Tsuda H, Nagano S, Koike M, Ikeuchi T, Hasegawa M, Papa S, Nagai Y, Mochizuki H, Baba K

Arm movements induced by noninvasive optogenetic stimulation of the motor cortex in the common marmoset

Ebina T, Obara K, Watakabe A, Masamizu Y, Terada S, Matoba R, Takaji M, Hatanaka N, Nambu A, Mizukami H, Yamamori T, Matsuzaki M

A Bayesian psychophysics model of sense of agency

Roberto Legaspi, Taro Toyoizumi

Intrinsic spine dynamics are critical for recurrent network learning in models with and without autism spectrum disorder

Humble J, Hiratsuka K, Kasai H, Toyoizumi T

Theta Oscillations Alternate With High Amplitude Neocortical Population Within Synchronized States

Munro Krull E, Sakata S, Toyoizumi T

Parkinson's disease is a type of amyloidosis featuring accumulation of amyloid fibrils of α-synuclein.

Araki K, Yagi N, Aoyama K, Choong C, Hayakawa H, Fujimura H, Nagai Y, Goto Y, Mochizuki H

Tau binding protein CAPON induces tau aggregation and neurodegeneration

Hashimoto S, Matsuba Y, Kamano N, Mihira N, Sahara N, Takano J, Muramatsu S, Saido T, Saito T

Rational Engineering of XCaMPs, a Multicolor GECI Suite for In Vivo Imaging of Complex Brain Circuit Dynamics

Inoue M, Takeuchi A, Manita S, Horigane S, Sakamoto M, Kawakami R, Yamaguchi K, Otomo K, Yokoyama H, Kim R, Yokoyama T, Takemoto-Kimura S, Abe M, Okamura M, Kondo Y, Quirin S, Ramakrishnan C, Imamura T, Sakimura K, Nemoto T, Kano M, Fujii H, Deisseroth K, Kitamura K, Bito H

Common marmosets (Callithrix jacchus) evaluate third-party social interactions of human actors but Japanese monkeys (Macaca fuscata) do not.

Kawai Nobuyuki, Nakagami Akiko, Yasue Miyuki, Koda Hiroki, Ichinohe Noritaka